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Concomitant use or discontinuation of CYP450 isoenzymes including CYP450 3A4 inducers, CYP450 3A4 inhibitors, or CYP450 2D6 inhibitors are intricate; concomitant use necessitates watchful consideration of the results to the guardian drug, tramadol, as well as active metabolite, M1.Bensedin, often called diazepam, is usually a benzodiazepine drugs.

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